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yxaA [2017-8-11 16:0:3]
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yxaA [2017-8-11 16:0:3]

putative glycerate kinase
locus
BSU40040
pI
4.53
mw
39.24 kDa
protein length
382 aa Sequence Blast
gene length
1146 bp Sequence Blast
function
unknown
product
putative glycerate kinase
essential
no
ec
2.7.1.31
synonyms
glxK
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 6|Groups of genes] → [category|SW 6.6|Poorly characterized/ putative enzymes]

    • Gene

    Coordinates
    4,112,073 → 4,113,221

    The protein

    Catalyzed reaction/ biological activity

  • ATP + (R)-glycerate = ADP + 3-phospho-(R)-glycerate (according to Swiss-Prot)

    • Protein family

  • glycerate kinase type-1 family (according to Swiss-Prot)

    • Structure

  • [PDB|3CWC] (from Salmonella Typhimurium 58% identity)

    • Expression and Regulation

    Operons

    genes
    [gene|4907D4585491349E2592B0EF9150312A80785EE5|yxaA]-[gene|9A223AE85131511B7EA3A71EA57D87E8B167FA67|yxaB]
    description
    [Pubmed|15805528,10746760]

    sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|15805528], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]
  • [protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB]: sigma factor, [Pubmed|15805528], in [regulon|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB regulon]

    • regulatory mechanism

  • [protein|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB]: repression, [Pubmed|15805528,18326573], in [regulon|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB regulon]

    • regulation

  • induced by stress ([protein|search|SigB]) [Pubmed|15805528]
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    Biological materials

    Mutant

  • MGNA-B680 (yxaA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1679 NBRP B. subtilis, Japan]

    • References

  • 10746760